HoloImmune - Adaptogenic ParaProbiotic

HoloImmune - Adaptogenic ParaProbioticAdaptogenic ParaProbiotic For Smarter and Balanced Immune System Build a stronger and smarter immune system with HoloImmune by Healthy Gut. Backed by over 36 clinical studies, this premium adaptogenic supplement features breakthrough paraprobiotic technology using heat killed probiotic strains that safely survive harsh stomach acid to train your immune defenses directly in the gut. By perfectly balancing communication between your innate and adaptive

Adaptogenic ParaProbiotic

For Smarter and Balanced Immune System

Build a stronger and smarter immune system with HoloImmune by Healthy Gut. Backed by over 36 clinical studies, this premium adaptogenic supplement features breakthrough paraprobiotic technology using heat-killed probiotic strains that safely survive harsh stomach acid to train your immune defenses directly in the gut. 

By perfectly balancing communication between your innate and adaptive immune pathways, HoloImmune eliminates overreactive seasonal tissue responses, calms environmental allergen sensitivities, and relieves reactive skin irritations. 

Formulated with high-potency M-Gard Beta-Glucans and Immuse to optimize natural killer cells, this clean, hypoallergenic vegetable capsule promotes year-round respiratory health, oral comfort, and vital physical resilience against stress and age-related decline.

• Provides Intelligent Adaptogenic Immune Support: Delivers a balanced, measured immune response that ensures your body reacts precisely to actual environmental threats without overreacting or accidentally attacking its own healthy cells.
• Trains Defenses Where It Matters Most: Optimizes physical resilience by targeting the gut lining, where up to 80% of your body's active immune cells reside, making it the most critical training ground for daily defense.
• Corrects Five Major Immune System Malfunctions: Synchronizes complex internal signaling to naturally tune up or tune down pathways that have become too passive, too aggressive, or disorganized due to daily stress, life changes, or aging.
• Primes Innate Cellular Defenses: Incorporates premium M-Gard Beta-Glucans (1,3/1,6) from purified baker's yeast to activate key defensive cells and boost Secretory Immunoglobulin A (SIgA) levels in the gut lining, reinforcing your first line of defense while lifting your mood baseline and reducing temporary fatigue.
• Activates Master Immune Controllers: Utilizes Immuse (Lactococcus lactis JCM 5805), a highly advanced postbiotic backed by over 25 studies, to uniquely stimulate plasmacytoid dendritic cells (pDCs) which act as upstream master commanders to facilitate vital cross-talk between your innate and adaptive immune systems and support downstream Natural Killer (NK) cell activity.
• Balances Adaptive Immune Responses: Features Immuno-LP20 (Lactobacillus plantarum L-137), a heat-killed immunobiotic backed by over 12 years of research that successfully survives gastric transit to stimulate IL-12 production, helping to balance the vital ratio between Th1 and Th2 cells while providing broader documented benefits for oral gum health and general well-being.
• Calms Seasonal Tissue Reactivity: Employs Lactobacillus acidophilus L-92, a specialized heat-treated strain studied since 1985, to regulate Th1 and Th2 adaptive balance and lower markers of an overreactive innate immune system, making it highly effective at soothing seasonal tissue sensitivities caused by environmental allergens.
• Relieves Skin Immune Reactions: Works from the inside out to stabilize tissue pathways, promoting clear, comfortable, and balanced skin that is less reactive to external triggers.
• Maintains Upper Respiratory Comfort and Vitality: Supports optimal comfort in the nose, throat, and chest during seasonal shifts, helping to keep your breathing clear and minimizing occasional physical weariness.
• Ensures Superior Shelf Stability and Gut Survival: Utilizes advanced paraprobiotic cell wall lysates rather than fragile live bacteria, guaranteeing that the ingredients remain exceptionally stable on the shelf and safely navigate harsh stomach acid to interact directly with intestinal tissue.
• Clean Label Allergen Free Capsule Delivery: Encapsulated strictly in plant-derived Hypromellose vegetable capsules with zero synthetic colorants, chemical flow agents, or hidden fillers, providing a pure, non-GMO formula you can trust completely.

Details

This premium oral dietary supplement features a highly advanced matrix of purified beta-glucans and scientifically standardized paraprobiotics. Formulated in clean vegetable capsules, this targeted blend optimizes innate cellular defenses, supports upper respiratory tract comfort, and coordinates a balanced immune system baseline. Free from common allergens and synthetic fillers, it delivers stable, heat-treated microbial strains that survive the gastric passage to provide consistent, long-term physical resilience.

Benefits of Ingredients

• M-Gard Beta-Glucans: Cellular pathway priming. Optimizes innate defenses and systemic immune readiness.
• Lactococcus lactis (Immuse): Dendritic cell activation. Signals comprehensive, high-level defensive responses. Triggers master pDC cells to coordinate innate and adaptive immune cross-talk.
• Lactobacillus plantarum (Immuno-LP20): Stable cell wall lysate interaction. Eases daily fatigue and supports upper respiratory health. Regulates Th1 and Th2 balance, supports oral health, and eases daily fatigue.
• Lactobacillus acidophilus (L-92): Immune signaling balancing. Calms environmental allergen reactivity and promotes clear skin comfort.
  

5 Common Immune System Malfunctions

We all nee a strong AND smart immune system, that is attuned to our environment and not at war with it. To have the appropriate responses to the current environment. No extra effort that can accidentally attack our own cells.

1. Under-Active Innate Immunity (too passive)
2. Overactive Innate Immunity (too aggressive)
3. Poor Communication between Innate and Adaptive immune systems (disorganized)
4. Under-Active Adaptive Immunity (not smart enough)
5. Overactive Adaptive Immunity (too destructive).

Any one of these 5 patterns can get triggered with stress, life changes or aging. To make matters more confusing, sometimes more than one pattern is happening at the same time.

Which is why taking an adaptogenic immune support product can be so helpful. Adaptogenic ParaProbiotics can help tune up or tune down the patterns that will guide us into more balance.

In the end we want a healthy immune system that creates a measured response that is not too harsh or too light.

HoloImmune’s four unique ingredients work synergistically to help regulate these 5 immune pathways. 

Ingredients

Contains:

• Beta glucans (M-Gard from Saccharomyces cerevisiae)
• Resililence Builder Blend (Lactococcus lactis strain Plasma (Immuse - Paraprobioitc), Lactobacillus plantarum (Immuno-LP20), Lactobacillus acidophilus strain (L-92).

Other Ingredients:
Vegetable Capsule (Hypromellose), Microcrystalline cellulose.

Instructions

Directions for Use

Take one capsule/day with food or as directed by your health practitioner.

Storage:
Keep tightly closed in a cool, dry place in original container. Do not expose to excessive heat.

Caution:
Speak with your healthcare provider before using, especially if you have a health condition, take medications, are pregnant or nursing.

Recommended Use

Adaptogenic immune, gut lining, and respiratory comfort support, activates master controllers, balances adaptive responses, and calms seasonal tissue and/or skin reactions.

Scientific References

Scientific References: Probiotics and Prebiotics