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Description
Biotinylated PD-L1 Fc&Avi Tag Protein, MouseProduct Specification Species Mouse Synonyms PD L1, B7 homolog 1 (B7 H1), CD274 Accession Q9EP73 Amino Acid Sequence Phe19 Thr238, with C terminal Human IgG1 Fc & Avi Tag
Product Specification
| Species | Mouse |
| Synonyms | PD-L1, B7 homolog 1 (B7-H1), CD274 |
| Accession | Q9EP73 |
| Amino Acid Sequence | Phe19-Thr238, with C-terminal Human IgG1 Fc & Avi Tag FTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 72-83kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Human Fc Tag, Avi Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Azuma T. et al. (2008) B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. Blood. 111: 3635. |
Background
Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. Mature mouse B7-H1 consists of a 221 amino acid (aa) extracellular domain (ECD) with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 30 aa cytoplasmic domain. B7-H1 is expressed on inflammatory-activated immune cells including macrophages, T cells, and B cells, keratinocytes, endothelial and intestinal epithelial cells, as well as a variety of carcinomas and melanoma. B7-H1 binds to T cell B7-1/CD80 and PD-1. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells.
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Exchange/Return Notes
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4.8 ★★★★★
Based on 1050 reviews
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Product Reviews
★★★★★ 5
Nice Ball!!
Size: 6 Inch, Color: Red, Size: 6 Inch, Color: Red
Brinkley my Golden doodle loves her ball. Carries it everywhere. Its holding up pretty well. And the tabs make it easy to play tugga war.
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Reviewed in the United States on May 16, 2026
★★★★★ 5
Boston terrier
Size: 6 Inch, Color: Red
My bostie loves to grab the tabs and toss this around! Well made. Can be chewed on and it holds up. Fun toy.
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Reviewed in the United States on March 12, 2026
★★★★★ 5
Wonderful
Size: 9 Inch, Color: Red
Just bought my second one for my German shepherd. 1st one I bought a year ago. She managed to pop it within a few days. She still was able to play with it by grabbing ahold of the straps. Takes it everywhere. We call it her tether ball. Should've seen her when we got the new one out of the box. Hasn't left it alone since.
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Reviewed in the United States on April 14, 2026
★★★★★ 4
Keeps him busy. Puppy proof
Size: 6 Inch, Color: Independence Day
Thankfully I bought 2. One of the pumps broke as I was trying to blow up. That is the reason i did not give then 5 stats. This is a great toy for my puppy. Keeps him entertained and is pretty sturdy.
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Reviewed in the United States on April 30, 2026
★★★★★ 5
Great for dog self play
Size: 6 Inch, Color: Red, Size: 6 Inch, Color: Red
So much fun for my puppy. Easy to grab and throw for him to play alone. Durable for a medium dog. This is his favorite toy. I also bought one for my friends cattle dog puppy who went bonkers with it. Yet her dog liked to chew the tags off. So I wouldn’t recommend for chewers.
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Reviewed in the United States on May 27, 2026