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Description
Biotinylated Siglec-4a His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms MAG, Siglec 4a, GMA, S MAG Accession P20916 1 Amino Acid Sequence Gly20 Pro516, with C terminal 10*His&Avi tag
Product Specification
| Species | Human |
| Synonyms | MAG, Siglec-4a, GMA, S-MAG |
| Accession | P20916-1 |
| Amino Acid Sequence | Gly20-Pro516, with C-terminal 10*His&Avi tag GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPGGGSGGGSHHHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Läubli H. et al. (2020) Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses, Cellular and Molecular Life Sciences.77: 593-605. |
Background
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are cell surface receptors of the I-type lectin family that are expressed on innate immune cells and bind to sialylated and non-sialylated ligands. Myelin-Associated Glycoprotein (MAG), also known as Siglec-4a, is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. It is selectively expressed by myelinating cells including Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). It is encoded by a single gene that is conserved among vertebrates. It is composed of an extracellular segment containing five Ig-like domains, a single transmembrane segment, and a cytoplasmic domain. Mature MAG exists as two isoforms, termed S-MAG (short) and L-MAG (long), due to alternative splicing of the cytoplasmic domain.
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Love Sunbum!!!!
Style: Original
Best combo ever! I use this combo every beach day, and most days in general. I love how well it travels and that there is something for every need! The bag it comes in is such a plus too! Great quality and brand!
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Reviewed in the United States on May 4, 2026
★★★★★ 5
Sun Bum Reef friendly get it now!!!!!
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I love travel size sun bum sun screen. You need sun screen everyday!!! Sun bum is reef friendly everyone needs to use SUN BUM!!!!!
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Reviewed in the United States on May 12, 2026
★★★★★ 5
Sun Bum kit a saver!!
Style: Mineral
Great little bag full of sunscreen for my grandson. Glad we had it to take it everywhere with us. A little pricey but he needs it so instead of taking bunches of bottles we had this.
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Reviewed in the United States on May 21, 2026
★★★★★ 4
Sunscreen is great, I would t recommend the chapstick
Style: Original
Sun Bum is hands down the best sunscreen I’ve ever used. It smells incredible, like a tropical vacation with that perfect coconut scent. It goes on smoothly, doesn’t leave you feeling sticky or greasy, and actually works! As long as I reapply every few hours, I don’t get burned, which is more than I can say for most other sunscreens I’ve tried.
The face stick is good, goes on easily, but is a little greasy feeling.
I do not like the chapstick, I can’t keep the taste of it out of my mouth and I feel like you have to put it on again and again.
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Reviewed in the United States on July 15, 2025
★★★★★ 5
Perfect!
Style: Original
Perfect for that carry on to a sunny place!!
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Reviewed in the United States on May 18, 2026