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Description
Researched Nutritionals Circadian PM CapsulesCircadian PM features PharmaGABA, the natural form of GABA, made through a natural fermentation process. This results in a superior form of GABA vs other synthetic options. Synthetic forms of GABA are less bio available, as their molecular size is too large to pass the blood brain barrier. PharmaGABA is easily absorbed and binds to GABA receptors in the peripheral nervous system, activating the parasympathetic nervous system. This activation of the
Circadian PM features PharmaGABA, the natural form of GABA, made through a natural fermentation process. This results in a superior form of GABA vs other synthetic options. Synthetic forms of GABA are less bio-available, as their molecular size is too large to pass the blood-brain barrier. PharmaGABA is easily absorbed and binds to GABA receptors in the peripheral nervous system, activating the parasympathetic nervous system. This activation of the parasympathetic nervous system by PharmaGABA is measurable within 5 to 30 minutes after ingestion.*
The unique blend of herbs, nutrients, and amino acids make Circadian PM a must-have formulation for patients dealing with sleep challenges and those who want to improve the quality of their sleep utilizing natural methods.
- Calming PM Formula - A multifaceted approach is needed to aid in falling asleep faster, staying asleep longer, and achieving higher quality rest. Circadian PM utilizes a blend of 10 ingredients, promoting multiple mechanisms of action to nurture healthy sleep and promote nighttime stress management.*
- GABA Nervous System Support - Promotes a healthy central nervous system and initiation in falling asleep by increasing GABA (gamma-aminobutyric acid), the primary inhibitory central nervous system neurotransmitter. This product's GABA supplement is in the form of premium PharmaGABA.*
- Supports Healthy Histamine Levels to Reduce Wakefulness - Includes HistaCalm blend to help reduce wakefulness by supporting healthy histamine levels in the brain. Promotes normal cytokine function to relax the central nervous system, leading to a healthy pain response.*
- Supports Stress Management at Night - CalmMind is a proprietary blend that includes magnolia bark extract, valerian root, 5 HTP, turmeric extract, lemon balm extract, and an L-theanine supplement. Circadian PM also promotes normal cytokine function to relax the central nervous system.*
- Vegan and Non-GMO - Manufactured without milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, corn and gluten. Produced in a facility that may process other ingredients with these allergens. Researched Nutritionals nervous system supplements and stress management supplements are professional-grade formulations.
*This is a statement of nutritional support. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases. Individual results may vary.
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Exchange/Return Notes
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4.6 ★★★★★
Based on 510 reviews
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Product Reviews
★★★★★ 4
Great for chewing but very sharp and mangled in a few days
Color: Blue Gator, Size: 1 Count, Color: Blue Gator, Size: 1 Count
I thought this was a fantastic idea having baking soda added for fresh clean teeth while enjoying a new toy. I wanted to review 2 main things about this.
First, if my dog enjoyed this toy. That answer would be yes absolutely! She is chewing it as I’m writing this right now. She can spend a good amount of time chewing away on this and it keeps her busy without having to use a rawhide treat which we only try to use if we re going to be gone for longer then 4 hours. The kids love playing fetch with her and she stays engaged the whole time. It is very heavy and when being thrown can become a weapon so I always supervise!
Last, the durability of the toy. So it is durable but not completely. As you can see the toy got very sharp where she has been chewing it and I’ve even noticed a little blood on it which means it’s cutting her gums. It wasn’t a large enough amount for me to take it away. It is still almost the exact same size but maybe after a month I will re edit this for more accurate on durability since it’s only been about a week that she has gotten it.
Overall, I would recommend this toy it’s a great price and keeps her attention a lot more then other toys I spent twice the amount of money on!
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Reviewed in the United States on March 9, 2022
★★★★★ 3
Too Hard
Color: Blue T-Bone, Size: 1 Count
I have a pit puppy, 20 lbs, who loves to chew. She's huge for her age, and I wanted to get her a new toy. I bought two different toys, hoping she would like one. The other toy was a hit, they both jumped at it and were excited about it, probably because it had rawhide rings that went with it. This one was immediately thrown to the side, even though my pit loves to chew on non edible toys. I think this one was just too hard, because both her, and my Chihuahua-Jack Russell, weren't interested. It didn't have any smell to attract them, which is why I bought it, because they love peanut butter stuff. I'm not going to go as far as to lick it and taste it... I'm pretty sure it won't taste like peanut butter, either. I feel so bad for my little pittie, she's just sitting here with a sad look on her face because my other dog stole the fun chew toy. I've immediately ordered another of one of those so they both have one, but I've just money wasted on this one. It's probably better they don't like it, I'd be worried about them breaking their teeth. I know it's supposed to be for power chewers, but it has no give whatsoever, just extremely hard, shiny plastic. It's useless, unless you're planning on filing it into a point and making a prison shank. Maybe you can leave it in front of the fridge for your SO to step on in the middle of the night when he goes to steal your almond milk. I'll figure out some way to use it. I did dip it into my boyfriend's peanut butter jar to let my puppy lick it, but I can do that with a spoon. I wanted her to feel like she got something, maybe my other dog will let her have a turn with the fun toy after awhile. That's the only reason I gave it 3 stars. You can dip it in peanut butter and I was being generous.
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Reviewed in the United States on March 27, 2022
★★★★★ 5
Can become brittle with sharp edges with use.
Color: Blue T-Bone, Size: 1 Count
Our little dog loved chewing this, however after chewing the toy became jagged and brittle with sharp edges that cut into her upper lip which took about 2 weeks to heal. Unfortunately the return window had closed.
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Reviewed in the United States on March 10, 2026
★★★★★ 5
Busy bone
Color: Blue T-Bone, Size: 1 Count, Color: Blue T-Bone, Size: 1 Count
My dog loves these!! Great busy bone! And they can hold it with her paws really well. It does kill your foot if you step on it barefoot in the middle of the night. This is a picture of the bone after 7months.
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Reviewed in the United States on June 1, 2026
★★★★★ 5
My Dog Loves this!
Color: Blue T-Bone, Size: 1 Count, Color: Blue T-Bone, Size: 1 Count
My dog loves her Nubbies! My Dog chews her Nubbie every morning after she has her breakfast. She sometimes wants my husband or I to hold it for her while she chews on it. I think it is really good for her teeth and gums. These last a few months for our dog who chews it every morning. After a few months the edges get a little rough from all the chewing so I throw it out and replace with a new one. These are very reasonably priced, so I always have a fresh one ready to go. She gets very excited when we get a new one out of the package..
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Reviewed in the United States on September 5, 2025