Nucleoprotein His tag, HRSVB (Strain 18537)
SKU: 2095439116

Nucleoprotein His tag, HRSVB (Strain 18537)

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Description

Nucleoprotein His tag, HRSVB (Strain 18537)Product Specification Species HRSV Synonyms Nucleoprotein, Protein N, Nucleocapsid protein Accession P24566 Amino Acid Sequence Met1 Leu391, with N terminal 8*His

Product Specification


Species HRSV
Synonyms Nucleoprotein, Protein N, Nucleocapsid protein
Accession P24566
Amino Acid Sequence Met1-Leu391, with N-terminal 8*His MHHHHHHHHMALSKVKLNDTLNKDQLLSSSKYTIQRSTGDNIDTPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILKDAGYHVKANGVDITTYRQDINGKEMKFEVLTLSSLTSEIQVNIEIESRKSYKKLLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEIKRYKGLIPKDIANSFYEVFEKHPHLIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGSGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKEDDVEL
Expression System E.coli
Molecular Weight 43kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM PB, 150mM NaCl, 1mM EDTA, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Reference

1、Oliveira A P. et al. (2013) Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells. Virus Res. 177(1): 108-112.

2、Céspedes P F. et al. (2014) Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells. Proc Natl Acad Sci U S A. 111(31): E3214.

Background

Human Respiratory Syncytial Virus (HRSV) is a negative-sense single-stranded RNA virus that belongs to the Paramyxoviridae family and the Pneumovirinae subfamily, and considered the most important pathogen causing respiratory disease in infants and neonates worldwide. The nucleoprotein of HRSV, a canonical cytosolic protein, is highly conserved among pneumoviruses and interacts with viral RNA, generating a helicoidal nucleocapsid which is responsible for genome and anti-genome resistance to RNase. In addition, the nucleoprotein could be responsible for inhibiting T-cell activation during infection by HRSV, and expressed on the surface of epithelial and dendritic cells, preventing immunological synapse assembly by naïve CD4+ T cells. Therefore, this protein is defined as a major virulence factor that contributes to impairing acquired immunity and enhances susceptibility to reinfection by HRSV.
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SKU: 2095439116

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I like the convenience of paper plates and these large 34 oz. bowls are perfect for microwave cooking. They are deep enough to handle soup, pasta, stuffing and vegetable sides with no problems and without any leaking, and are a good value for the price. They look stylish and make clean up less of a chore. You can't go wrong with Dixie paper products. They're sturdy, fun, and last through the meal.
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Style: 34 Ounces, Size: 34 Count
Great product great for salads they are sturdy and well made.
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Good size for a serving bowl.
Style: 34 Ounces, Size: 34 Count
Nice large bowl. Can be used as a serving bowl. Nice design and sturdy. I have subscribed to receive a pack once a month.
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Reviewed in the United States on May 26, 2026
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