Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
ATF3 Recombinant Rabbit mAb (S-3904)Product Specification Host Rabbit Antigen ATF3 Synonyms Cyclic AMP dependent transcription factor ATF 3; cAMP dependent transcription factor ATF 3; Activating transcription factor 3 Location Nucleus Accession P18847 Clone Number S 3904 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms Positive Sample HeLa, HepG2, HCT 116, 293T, LNCaP, RAW264. 7 Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | ATF3 |
| Synonyms | Cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3; Activating transcription factor 3 |
| Location | Nucleus |
| Accession | P18847 |
| Clone Number | S-3904 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms |
| Positive Sample | HeLa, HepG2, HCT 116, 293T, LNCaP, RAW264.7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:500 | Hu |
| ICC | 1:500 | Hu, Ms |
Background
ATF3 (Activating Transcription Factor 3) is a 181-amino-acid stress-inducible bZIP transcription factor that binds DNA as homo- or heterodimer, recognized by the consensus TGACGTCA, and acts as a dual-function transcriptional regulator—repressing or activating target genes involved in apoptosis, inflammation, cell-cycle checkpoints, metabolic reprogramming and oncogenesis—rapidily up-regulated in response to hypoxia, DNA damage, cytokines, ER stress or mechanical strain, frequently overexpressed in cancers where it promotes survival, metastasis and chemoresistance yet can also function as a tumor suppressor depending on cellular context, and is subject to tight control via MAPK, NF-κB, p53 and multiple feedback loops, making it a critical node in integrating stress signals and determining cell fate.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy