Histone H3 (tri methyl K4) Recombinant Rabbit mAb (S-4099)
SKU: 79594471885

Histone H3 (tri methyl K4) Recombinant Rabbit mAb (S-4099)

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Description

Histone H3 (tri methyl K4) Recombinant Rabbit mAb (S-4099)Product Specification Host Rabbit Antigen Histone H3 (tri methyl K4) Synonyms H3K4me3 Location Nucleus Accession P68431 Clone Number S 4099 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, ChIP Reactivity Hu, Ms, Rt Positive Sample HeLa, NIH 3T3, C6 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12

Product Specification


Host Rabbit
Antigen Histone H3 (tri methyl K4)
Synonyms H3K4me3
Location Nucleus
Accession P68431
Clone Number S-4099
Antibody Type Recombinant mAb
Isotype IgG
Application WB, ICC, ChIP
Reactivity Hu, Ms, Rt
Positive Sample HeLa, NIH/3T3, C6
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20°C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt
ICC 1:500 Hu, Ms
ChIP 1:20-1:50 Hu

Background

Histone H3 lysine 4 trimethylation (commonly denoted as H3K4me3) is a crucial epigenetic modification on the tail of core histone H3 that plays a central role in regulating gene transcription. It is primarily catalyzed by histone methyltransferases from the COMPASS/COMPASS-like family (such as MLL1-4 and SET1A/B) and is specifically recognized by "reader" proteins containing PHD domains (e.g., Taf3 and ING family proteins). The genomic distribution of H3K4me3 is highly characteristic: it is strongly enriched at the promoter regions of actively transcribed genes, particularly near transcription start sites, marking a "primed for activation" state. This modification facilitates the formation of open chromatin structures and the assembly of the transcription initiation complex by recruiting chromatin remodelers, general transcription factors, and histone acetyltransferases, thereby positively regulating gene expression. H3K4me3 is essential for maintaining pluripotency in embryonic stem cells, cell fate determination, and processes such as learning and memory. Notably, its dysregulation—whether excessive or deficient—is closely associated with various developmental disorders and cancers (such as leukemia and breast cancer). Consequently, H3K4me3 is not only a vital biomarker in fundamental research but also a potential target for disease diagnosis and therapy.

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SKU: 79594471885

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Richard G.
Natrona Heights, US
★★★★★ 4
Works well...but the price!
I ordered two sets to connect 3 monitors together for a workstation at my job. These are well designed and the magnets are pretty strong. Installation is easy and it holds the alignment well. The only issue is the price. For what it is, the price is quite high. The value proposition would be much higher for those who need to be able to not have them aligned from time to time, such as rotating one around for others to see in an office. But if don't need to do this and just want alignment, there are much cheaper options. If you want to go the cheapest DIY route and it won't be seen, some popsicle sticks with two sided tape works well. You can crack them in the middle to act as a hinge.
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Reviewed in the United States on February 5, 2026
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Verified Purchase
Kayla m
Draper, US
★★★★★ 5
Awesome product only thing that worked
I originally thought the Screen Buddy was overpriced, but after spending hundreds of dollars trying to perfectly align my monitors for sim racing, this is genuinely the only thing that has actually worked properly. Triple monitor alignment is one of the most frustrating parts of building a sim rig, especially with monitor arms constantly moving or sagging. This finally made everything line up the way I wanted. Expensive? Maybe. Worth it after all the headaches? Absolutely. Great job.
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Reviewed in the United States on May 9, 2026
M
Verified Purchase
medic4life
Grantham, US
★★★★★ 1
Doesn't stick
The adhesive tape kept coming off. I cleaned and followed the installation instructions, but it still kept coming off. Wouldn't recommend.
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Reviewed in the United States on April 23, 2026
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Verified Purchase
Ronald M.
Houston, US
★★★★★ 5
Works Great, Very happy customer
I’ve tried a few different ways to connect and manage dual monitors, and the Screen Buddy Dual Monitor Connector is easily one of the most straightforward and reliable solutions I’ve used. Setup was quick—no confusing instructions or extra headaches Performance-wise, it’s been rock solid. The connection stays stable and even when I bumped the monitors once, and they disconnected, it was a quick push and they clicked right back together. Build quality feels solid and durable, not flimsy like some cheaper connectors. It’s clearly designed with everyday users in mind, whether you’re working, gaming, or multitasking across multiple apps. Overall, it delivers exactly what it promises: a simple, dependable way to keep your screens connected with no gaps or one being too high or too low. Definitely worth it if you want a clean, hassle-free dual monitor setup.
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Reviewed in the United States on May 3, 2026
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Josh A. Carie
Chelsea, US
★★★★★ 3
Warning, if you have two different thickness of monitors these may not work as intended.
The product seems very well made and the adhesive is very strong. These seem like they would work really well if you have two monitors of the same thickness, in my case I did not and they actually created more of a gap then without.
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Reviewed in the United States on January 13, 2026

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